Hipk1 homeodomain interacting protein kinase 1 [ Mus musculus (house mouse) ] - Gene - Data resources

15257

Hipk1 homeodomain interacting protein kinase 1 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 15257)

Symbol: Hipk1

Full name: homeodomain interacting protein kinase 1

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: 1110062K04Rik; Myak

Summary: Predicted to enable protein serine/threonine kinase activity; protein tyrosine kinase activity; and transcription corepressor activity. Involved in adherens junction assembly; camera-type eye morphogenesis; and neuron differentiation. Acts upstream of or within several processes, including anterior/posterior pattern specification; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; and smoothened signaling pathway. Located in PML body; cytoplasm; and nuclear speck. Is expressed in several structures, including forebrain ventricular layer and future forebrain. Orthologous to human HIPK1 (homeodomain interacting protein kinase 1). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Ubiquitous expression in thymus adult (RPKM 35.2), testis adult (RPKM 31.7) and 28 other tissues

Orthologs: human

Gene size: 52080bp

Exon count: 19