BTLA B and T lymphocyte associated [ Homo sapiens (human) ] - Gene - Data resources

151888

BTLA B and T lymphocyte associated [ Homo sapiens (human) ]
Source: NCBI Gene (ID 151888)

Symbol: BTLA

Full name: B and T lymphocyte associated

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: BTLA1; CD272

Summary: This gene encodes a member of the immunoglobulin superfamily. The encoded protein contains a single immunoglobulin (Ig) domain and is a receptor that relays inhibitory signals to suppress the immune response. Alternative splicing results in multiple transcript variants. Polymorphisms in this gene have been associated with an increased risk of rheumatoid arthritis. [provided by RefSeq, Aug 2011]

Expression: Biased expression in lymph node (RPKM 5.9), appendix (RPKM 3.2) and 7 other tissues

Orthologs: mouse

Gene size: 35659bp

Exon count: 6