Full name: hypocretin

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: PPOX

Summary: This gene encodes a hypothalamic neuropeptide precursor protein that gives rise to two mature neuropeptides, orexin A and orexin B, by proteolytic processing. Orexin A and orexin B, which bind to orphan G-protein coupled receptors Hcrtr1 and Hcrtr2, function in the regulation of sleep and arousal. This neuropeptide arrangement may also play a role in feeding behavior, metabolism, and homeostasis. [provided by RefSeq, Sep 2015]

Expression: Biased expression in testis adult (RPKM 1.4), CNS E18 (RPKM 0.7) and 7 other tissues

Gene size: 1239bp

Exon count: 2