Full name: lipase I

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: CT17; LPDL; PLA1C; PRED5; mPA-PLA1 beta

Summary: The protein encoded by this gene is a phospholipase that hydrolyzes phosphatidic acid to produce lysophosphatidic acid. Defects in this gene are a cause of susceptibility to familial hypertrigliceridemia. This gene is also expressed at high levels in Ewing family tumor cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]

Expression: Biased expression in thyroid (RPKM 1.4), endometrium (RPKM 0.3) and 2 other tissues

Gene size: 102144bp

Exon count: 12