Full name: goosecoid homeobox

Gene type: protein coding

RefSeq status: VALIDATED

Summary: Enables DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and RNA polymerase II-specific DNA-binding transcription factor binding activity. Involved in middle ear morphogenesis and negative regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including animal organ development; dorsal/ventral neural tube patterning; and signal transduction involved in regulation of gene expression. Part of transcription regulator complex. Is expressed in several structures, including alimentary system; forebrain; genitourinary system; limb; and sensory organ. Orthologous to human GSC (goosecoid homeobox). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Biased expression in limb E14.5 (RPKM 7.2), mammary gland adult (RPKM 4.0) and 6 other tissues

Gene size: 2028bp

Exon count: 3