Pdia3 protein disulfide isomerase associated 3 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 14827)
Source: NCBI Gene (ID 14827)
Symbol: Pdia3
Full name: protein disulfide isomerase associated 3
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: 58kDa; ERp57; ERp60; ERp61; Erp; Grp58; PDI; PDI-Q2; PI-PLC; PLC[a]; Plca
Summary: Predicted to enable several functions, including identical protein binding activity; protein disulfide isomerase activity; and protein-disulfide reductase (glutathione) activity. Acts upstream of or within cellular response to interleukin-7 and positive regulation of extrinsic apoptotic signaling pathway. Located in cell surface and endoplasmic reticulum. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and limb segment. Human ortholog(s) of this gene implicated in autoimmune hepatitis. Orthologous to human PDIA3 (protein disulfide isomerase family A member 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Ubiquitous expression in placenta adult (RPKM 203.6), ovary adult (RPKM 132.6) and 28 other tissues
Orthologs: human
Gene size: 24786bp
Exon count: 13