Gabrb2 gamma-aminobutyric acid (GABA) A receptor, subunit beta 2 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 14401)
Source: NCBI Gene (ID 14401)
Symbol: Gabrb2
Full name: gamma-aminobutyric acid (GABA) A receptor, subunit beta 2
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: C030002O17Rik; C030021G16Rik; Gabrab2; Gabrb-2
Summary: Enables transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential. Contributes to GABA-gated chloride ion channel activity. Involved in several processes, including inner ear development; nervous system development; and sensory perception of sound. Located in plasma membrane. Is active in GABA-ergic synapse. Is integral component of postsynaptic specialization membrane. Is expressed in several structures, including alimentary system; heart; integumental system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in autistic disorder and developmental and epileptic encephalopathy 92. Orthologous to human GABRB2 (gamma-aminobutyric acid type A receptor subunit beta2). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in cerebellum adult (RPKM 18.5), cortex adult (RPKM 14.5) and 5 other tissues
Orthologs: human
Gene size: 213077bp
Exon count: 12