Gabra3 gamma-aminobutyric acid (GABA) A receptor, subunit alpha 3 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 14396)
Source: NCBI Gene (ID 14396)
Symbol: Gabra3
Full name: gamma-aminobutyric acid (GABA) A receptor, subunit alpha 3
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: Gabra-3
Summary: Enables transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in several processes, including GABAergic synaptic transmission; chloride transmembrane transport; and gamma-aminobutyric acid signaling pathway. Predicted to act upstream of or within ion transport. Located in GABA-ergic synapse. Is integral component of postsynaptic specialization membrane. Is expressed in several structures, including alimentary system; brain; eye; genitourinary system; and immune system. Human ortholog(s) of this gene implicated in bipolar disorder and multiple sclerosis. Orthologous to human GABRA3 (gamma-aminobutyric acid type A receptor subunit alpha3). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in frontal lobe adult (RPKM 17.8), cortex adult (RPKM 14.7) and 10 other tissues
Orthologs: human
Gene size: 224244bp
Exon count: 13