Dtx1 deltex 1, E3 ubiquitin ligase [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 14357)
Source: NCBI Gene (ID 14357)
Symbol: Dtx1
Full name: deltex 1, E3 ubiquitin ligase
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Also known as: Fxit1; mKIAA4160
Summary: Predicted to enable Notch binding activity; ubiquitin protein ligase activity; and ubiquitin protein ligase binding activity. Acts upstream of or within several processes, including Notch signaling pathway; cellular response to leukemia inhibitory factor; and negative regulation of T cell differentiation. Predicted to be located in cytosol and nuclear body. Predicted to be active in nucleoplasm. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; genitourinary system; and sensory organ. Orthologous to human DTX1 (deltex E3 ubiquitin ligase 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in spleen adult (RPKM 82.7), CNS E18 (RPKM 30.0) and 14 other tissues
Orthologs: human
Gene size: 31488bp
Exon count: 11