WFDC3 WAP four-disulfide core domain 3 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 140686)
Source: NCBI Gene (ID 140686)
Symbol: WFDC3
Full name: WAP four-disulfide core domain 3
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Also known as: WAP14; dJ447F3.3
Summary: This gene encodes a member of the WAP-type four-disulfide core (WFDC) domain family. The WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor. The encoded protein contains four WFDC domains. Most WFDC genes are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the telomeric cluster. Alternatively spliced transcript variants have been observed but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]
Expression: Restricted expression toward testis (RPKM 19.8)
Orthologs: mouse
Gene size: 17671bp
Exon count: 7