Full name: coagulation factor XIII, beta subunit

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: Cf-13b; Cf13b

Summary: This gene encodes subunit B of the coagulation factor XIII that catalyzes the final step of the blood coagulation pathway. The encoded protein associates with subunit A to form a heterotetrameric protein that circulates in the plasma. During the blood coagulation process, thrombin-mediated proteolytic cleavage of the subunit A results in the dissociation of the encoded protein from the heterotetramer. Male mice lacking the encoded protein exhibit mild fibrosis together with hemosiderin deposits in the heart. [provided by RefSeq, Sep 2015]

Expression: Biased expression in liver E18 (RPKM 52.8), liver adult (RPKM 17.8) and 4 other tissues

Gene size: 22212bp

Exon count: 12