Full name: adhesion G protein-coupled receptor G4

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: GPR112; PGR17; RP1-299I16

Summary: This gene encodes a G-protein coupled receptor belonging to a large family of diverse integral membrane proteins that participate in various physiological functions. Members of this superfamily are characterized by a signature 7-transmembrane domain motif. The ligand for this family member is unknown, and it is therefore an orphan receptor. This receptor is known to be expressed in normal enterochromaffin cells and in gastrointestinal neuroendocrine carcinoma cells, and it is therefore considered to be a novel biomarker or target for immunotherapy. [provided by RefSeq, May 2010]

Expression: Biased expression in duodenum (RPKM 1.3), small intestine (RPKM 0.8) and 2 other tissues

Gene size: 115928bp

Exon count: 28