Dlx2 distal-less homeobox 2 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 13392)
Source: NCBI Gene (ID 13392)
Symbol: Dlx2
Full name: distal-less homeobox 2
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: DII A; Dlx-2; Tes-1
Summary: Enables DNA-binding transcription activator activity, RNA polymerase II-specific; chromatin binding activity; and nucleic acid binding activity. Involved in negative regulation of photoreceptor cell differentiation; positive regulation of amacrine cell differentiation; and positive regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including negative regulation of Notch signaling pathway; nervous system development; and skeletal system development. Located in nucleus. Is expressed in several structures, including branchial arch; embryo ectoderm; genitourinary system; sensory organ; and tooth. Orthologous to human DLX2 (distal-less homeobox 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in whole brain E14.5 (RPKM 11.5), CNS E14 (RPKM 10.5) and 5 other tissues
Orthologs: human
Gene size: 3347bp
Exon count: 3