Ackr1 atypical chemokine receptor 1 (Duffy blood group) [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 13349)
Symbol: Ackr1
Full name: atypical chemokine receptor 1 (Duffy blood group)
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: CCBP1; CD234; Darc; Dfy; ESTM35; FY; GPD
Summary: Predicted to enable C-C chemokine binding activity. Acts upstream of or within inflammatory response and regulation of chemokine production. Predicted to be located in endosome and membrane. Predicted to be integral component of membrane. Is expressed in several structures, including genitourinary system; hemolymphoid system; lung; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in Plasmodium vivax malaria and malaria. Orthologous to human ACKR1 (atypical chemokine receptor 1 (Duffy blood group)). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Broad expression in cerebellum adult (RPKM 65.4), liver E14.5 (RPKM 38.7) and 18 other tissues
Orthologs: human
Gene size: 1618bp
Exon count: 2