Dctn1 dynactin 1 [ Mus musculus (house mouse) ] - Gene - Data resources

13191

Dctn1 dynactin 1 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 13191)

Symbol: Dctn1

Full name: dynactin 1

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: DAP-150; DP-150; Glued; p150; p150-glued; p150<glued>

Summary: Enables microtubule binding activity. Acts upstream of or within melanosome transport. Located in cell leading edge and microtubule cytoskeleton. Part of protein-containing complex. Is expressed in brain; embryo; and head. Human ortholog(s) of this gene implicated in Perry syndrome; amyotrophic lateral sclerosis type 1; and distal hereditary motor neuronopathy type 7B. Orthologous to human DCTN1 (dynactin subunit 1). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Ubiquitous expression in cerebellum adult (RPKM 36.9), frontal lobe adult (RPKM 32.3) and 28 other tissues

Orthologs: human

Gene size: 34399bp

Exon count: 35