Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 13115)
Source: NCBI Gene (ID 13115)
Symbol: Cyp27b1
Full name: cytochrome P450, family 27, subfamily b, polypeptide 1
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: Cp2b; Cyp1; Cyp27b; Cyp40; P450c1; Pddr; Vdd1; Vddr; VddrI; Vdr
Summary: Enables calcidiol 1-monooxygenase activity. Involved in calcitriol biosynthetic process from calciol; response to vitamin D; and vitamin D catabolic process. Acts upstream of or within calcium ion transport. Located in mitochondrion. Is expressed in several structures, including lower jaw molar; metanephros; and testis. Used to study rickets. Human ortholog(s) of this gene implicated in hepatitis B; obesity; rickets; type 1 diabetes mellitus; and vitamin D-dependent rickets type 1A. Orthologous to human CYP27B1 (cytochrome P450 family 27 subfamily B member 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in kidney adult (RPKM 4.4), stomach adult (RPKM 0.7) and 5 other tissues
Orthologs: human
Gene size: 7783bp
Exon count: 9