Cyp21a1 cytochrome P450, family 21, subfamily a, polypeptide 1 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 13079)
Source: NCBI Gene (ID 13079)
Symbol: Cyp21a1
Full name: cytochrome P450, family 21, subfamily a, polypeptide 1
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: 21-OH; 21OH; 21OHA; 21OHB; CYP21OH-A; Cyp21; Cyp21-ps1; Cyp21B; Cyp21a2-ps; Cyp21a2ps; Oh21-1; Oh21-2
Summary: Predicted to enable 17-hydroxyprogesterone 21-hydroxylase activity; heme binding activity; and progesterone 21-hydroxylase activity. Predicted to be involved in progesterone metabolic process and steroid biosynthetic process. Predicted to be located in endoplasmic reticulum and membrane. Is expressed in several structures, including adrenal gland; lung; metanephros; spleen; and testis. Human ortholog(s) of this gene implicated in congenital adrenal hyperplasia. Orthologous to several human genes including CYP21A2 (cytochrome P450 family 21 subfamily A member 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Restricted expression toward adrenal adult (RPKM 8124.5)
Orthologs: human
Gene size: 3079bp
Exon count: 10