Full name: collagen type XV alpha 1 chain

Gene type: protein coding

RefSeq status: REVIEWED

Summary: This gene encodes the alpha chain of type XV collagen, a member of the FACIT collagen family (fibril-associated collagens with interrupted helices). Type XV collagen has a wide tissue distribution but the strongest expression is localized to basement membrane zones so it may function to adhere basement membranes to underlying connective tissue stroma. The proteolytically produced C-terminal fragment of type XV collagen is restin, a potentially antiangiogenic protein that is closely related to endostatin. Mouse studies have shown that collagen XV deficiency is associated with muscle and microvessel deterioration. [provided by RefSeq, May 2013]

Expression: Broad expression in placenta (RPKM 113.8), fat (RPKM 52.0) and 17 other tissues

Gene size: 159584bp

Exon count: 45