SGPP2 sphingosine-1-phosphate phosphatase 2 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 130367)
Source: NCBI Gene (ID 130367)
Symbol: SGPP2
Full name: sphingosine-1-phosphate phosphatase 2
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Also known as: SPP2; SPPase2
Summary: The protein encoded by this gene is a transmembrane protein that degrades the bioactive signaling molecule sphingosine 1-phosphate. The encoded protein is induced during inflammatory responses and has been shown to be downregulated by the microRNA-31 tumor suppressor. Alternative splice variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2016]
Expression: Broad expression in thyroid (RPKM 13.7), esophagus (RPKM 12.0) and 18 other tissues
Orthologs: mouse
Gene size: 138634bp
Exon count: 7