DRAM2 DNA damage regulated autophagy modulator 2 [ Homo sapiens (human) ] - Gene - Data resources

128338

DRAM2 DNA damage regulated autophagy modulator 2 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 128338)

Symbol: DRAM2

Full name: DNA damage regulated autophagy modulator 2

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: CORD21; PRO180; TMEM77; WWFQ154

Summary: The protein encoded by this gene binds microtubule-associated protein 1 light chain 3 and is required for autophagy. Defects in this gene are a cause of retinal dystrophy. In addition, two microRNAs (microRNA 125b-1 and microRNA 144) can bind to the mRNA of this gene and produce the disease state. [provided by RefSeq, Mar 2017]

Expression: Ubiquitous expression in lymph node (RPKM 29.0), spleen (RPKM 26.6) and 25 other tissues

Orthologs: mouse

Gene size: 22931bp

Exon count: 11