Full name: collagen, type XVIII, alpha 1

Gene type: protein coding

RefSeq status: VALIDATED

Summary: Predicted to enable identical protein binding activity. Predicted to be an extracellular matrix structural constituent. Acts upstream of or within several processes, including angiogenesis; endothelial cell morphogenesis; and positive regulation of endothelial cell apoptotic process. Located in basement membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Used to study pigment dispersion syndrome. Human ortholog(s) of this gene implicated in primary angle-closure glaucoma. Orthologous to human COL18A1 (collagen type XVIII alpha 1 chain). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Broad expression in liver adult (RPKM 128.4), liver E18 (RPKM 40.0) and 21 other tissues

Gene size: 114379bp

Exon count: 44