CNGA1 cyclic nucleotide gated channel subunit alpha 1 [ Homo sapiens (human) ] - Gene - Data resources

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CNGA1 cyclic nucleotide gated channel subunit alpha 1 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 1259)

Symbol: CNGA1

Full name: cyclic nucleotide gated channel subunit alpha 1

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: CNCG; CNCG1; CNG-1; CNG1; RCNC1; RCNCa; RCNCalpha; RP49

Summary: The protein encoded by this gene is involved in phototransduction. Along with another protein, the encoded protein forms a cGMP-gated cation channel in the plasma membrane, allowing depolarization of rod photoreceptors. This represents the last step in the phototransduction pathway. Defects in this gene are a cause of retinitis pigmentosa autosomal recessive (ARRP) disease. Multiple transcript variants have been found for this gene. [provided by RefSeq, Oct 2019]

Expression: Broad expression in liver (RPKM 2.5), small intestine (RPKM 1.6) and 17 other tissues

Orthologs: mouse

Gene size: 80705bp

Exon count: 13