Full name: cadherin 5

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: 7B4; Cd144; VE-Cad; VECD; VEcad; Vec

Summary: This gene encodes a member of the cadherin family of calcium-dependent glycoproteins that mediate cell adhesion and regulate many morphogenetic events during development. The encoded preproprotein is further processed to generate a mature protein. Mice lacking the encoded protein die in utero due to vascular insufficiency, caused by increased endothelial apoptosis. Multiple distinct genes of the cadherin family, including this gene, are found on chromosome 8. [provided by RefSeq, Oct 2015]

Expression: Biased expression in lung adult (RPKM 243.6), subcutaneous fat pad adult (RPKM 72.5) and 8 other tissues

Gene size: 42890bp

Exon count: 13