Full name: CD36 molecule

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: FAT; GPIV; Scarb3

Summary: Enables lipoprotein particle binding activity; lipoteichoic acid immune receptor activity; and low-density lipoprotein particle receptor activity. Involved in several processes, including lipid transport; regulation of gene expression; and regulation of reactive oxygen species metabolic process. Acts upstream of or within several processes, including phagocytosis; positive regulation of cytokine production; and response to bacterium. Located in several cellular components, including brush border membrane; external side of plasma membrane; and membrane raft. Is expressed in several structures, including Meckel's cartilage; axial skeleton; bone; hindlimb; and telencephalon. Used to study platelet-type bleeding disorder 10. Human ortholog(s) of this gene implicated in several diseases, including blood platelet disease (multiple); hemolytic-uremic syndrome; osteoarthritis; pulmonary tuberculosis; and type 2 diabetes mellitus. Orthologous to human CD36 (CD36 molecule). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Biased expression in subcutaneous fat pad adult (RPKM 144.0), heart adult (RPKM 110.7) and 5 other tissues

Gene size: 107270bp

Exon count: 18