Full name: AGBL carboxypeptidase 1

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: CCP4; FECD8

Summary: Polyglutamylation is a reversible posttranslational modification catalyzed by polyglutamylases that results in the addition of glutamate side chains on the modified protein. This gene encodes a glutamate decarboxylase that catalyzes the deglutamylation of polyglutamylated proteins. Mutations in this gene result in dominant late-onset Fuchs corneal dystrophy. [provided by RefSeq, Nov 2013]

Expression: Low expression observed in reference dataset

Gene size: 951857bp

Exon count: 29