C1qa complement component 1, q subcomponent, alpha polypeptide [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 12259)
Source: NCBI Gene (ID 12259)
Symbol: C1qa
Full name: complement component 1, q subcomponent, alpha polypeptide
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: Adic; C1q
Summary: Involved in several processes, including complement-mediated synapse pruning; microglial cell activation; and nervous system development. Acts upstream of or within complement activation, classical pathway. Located in postsynapse. Is expressed in brain; foot; genitourinary system; and pancreas. Used to study epilepsy and systemic lupus erythematosus. Human ortholog(s) of this gene implicated in glomerulonephritis. Orthologous to human C1QA (complement C1q A chain). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Ubiquitous expression in mammary gland adult (RPKM 87.8), spleen adult (RPKM 86.7) and 25 other tissues
Orthologs: human
Gene size: 2929bp
Exon count: 3