Bmpr1b bone morphogenetic protein receptor, type 1B [ Mus musculus (house mouse) ] - Gene - Data resources

12167

Bmpr1b bone morphogenetic protein receptor, type 1B [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 12167)

Symbol: Bmpr1b

Full name: bone morphogenetic protein receptor, type 1B

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: ALK-6; Acvrlk6; Alk6; BMPR-1B; BMPR-IB; CFK-43a; SKR6

Summary: This gene encodes a serine/threonine kinase that functions as a receptor for bone morphogenetic proteins (BMPs). The encoded protein is a type I receptor, and forms a complex of two type II and two type I receptors at the cell membrane. This complex signals downstream to activate SMAD transcriptional regulators. This signaling is important in skeletal and bone development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013]

Expression: Biased expression in limb E14.5 (RPKM 1.8), frontal lobe adult (RPKM 1.8) and 11 other tissues

Orthologs: human

Gene size: 335106bp

Exon count: 19