ALKBH2 alkB homolog 2, alpha-ketoglutarate dependent dioxygenase [ Homo sapiens (human) ]
Source: NCBI Gene (ID 121642)
Source: NCBI Gene (ID 121642)
Symbol: ALKBH2
Full name: alkB homolog 2, alpha-ketoglutarate dependent dioxygenase
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Homo sapiens
Also known as: ABH2
Summary: The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 and ALKBH3 (MIM 610603) are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine (Duncan et al., 2002 [PubMed 12486230]).[supplied by OMIM, Mar 2008]
Expression: Ubiquitous expression in ovary (RPKM 6.9), endometrium (RPKM 5.8) and 25 other tissues
Orthologs: mouse
Gene size: 5284bp
Exon count: 4