Blm Bloom syndrome, RecQ like helicase [ Mus musculus (house mouse) ] - Gene - Data resources

12144

Blm Bloom syndrome, RecQ like helicase [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 12144)

Symbol: Blm

Full name: Bloom syndrome, RecQ like helicase

Gene type: protein coding

RefSeq status: VALIDATED

Summary: Enables 3'-5' DNA helicase activity. Involved in G-quadruplex DNA unwinding and replication fork processing. Acts upstream of or within several processes, including DNA metabolic process; negative regulation of thymocyte apoptotic process; and regulation of DNA recombination. Located in chromosome; cytoplasm; and nucleus. Is expressed in several structures, including brain; genitourinary system; gut; hemolymphoid system gland; and mammary gland. Used to study Bloom syndrome. Human ortholog(s) of this gene implicated in Bloom syndrome. Orthologous to human BLM (BLM RecQ like helicase). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Biased expression in liver E14 (RPKM 7.3), liver E14.5 (RPKM 5.7) and 12 other tissues

Orthologs: human

Gene size: 80156bp

Exon count: 24