Full name: NK3 homeobox 2

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: Bapx1; NKX3.2; Nkx-3.2

Summary: Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of chondrocyte differentiation and negative regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including animal organ development; embryonic skeletal system development; and intestinal epithelial cell development. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; genitourinary system; and limb. Orthologous to human NKX3-2 (NK3 homeobox 2). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Biased expression in colon adult (RPKM 7.5), limb E14.5 (RPKM 5.4) and 6 other tissues

Gene size: 2738bp

Exon count: 2