Bach2 BTB and CNC homology, basic leucine zipper transcription factor 2 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 12014)
Source: NCBI Gene (ID 12014)
Symbol: Bach2
Full name: BTB and CNC homology, basic leucine zipper transcription factor 2
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: E030004N02Rik
Summary: Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in import into nucleus and negative regulation of transcription by RNA polymerase II. Acts upstream of or within regulation of transcription, DNA-templated. Located in nucleus. Is expressed in several structures, including central nervous system; limb bud; reproductive system; retina; and urinary system. Human ortholog(s) of this gene implicated in immunodeficiency 60. Orthologous to human BACH2 (BTB domain and CNC homolog 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Broad expression in whole brain E14.5 (RPKM 5.3), CNS E14 (RPKM 5.0) and 24 other tissues
Orthologs: human
Gene size: 347697bp
Exon count: 12