Atp2b2 ATPase, Ca++ transporting, plasma membrane 2 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 11941)
Source: NCBI Gene (ID 11941)
Symbol: Atp2b2
Full name: ATPase, Ca++ transporting, plasma membrane 2
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: D6Abb2e; Gena300; PMCA2; Tmy; dfw; jog; wms; wri
Summary: Enables calcium-dependent ATPase activity. Involved in cochlea development and regulation of cytosolic calcium ion concentration. Acts upstream of or within several processes, including animal organ development; cGMP metabolic process; and detection of mechanical stimulus involved in sensory perception of sound. Located in several cellular components, including apical plasma membrane; endoplasmic reticulum; and neuronal cell body. Is expressed in heart; labyrinthine zone; liver; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 12. Orthologous to human ATP2B2 (ATPase plasma membrane Ca2+ transporting 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in cortex adult (RPKM 49.9), cerebellum adult (RPKM 49.7) and 4 other tissues
Orthologs: human
Gene size: 298783bp
Exon count: 30