Full name: neurogenic differentiation 4

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: ATH-3; Atoh3; MATH-3; Math3; bHLHa4

Summary: This gene belongs to the neurogenic differentiation factor family and encodes a basic helix-loop-helix (bHLH) transcription factor which is expressed in the developing nervous system with high levels of expression in the brain, retina and cranial ganglions. Expression gradually becomes restricted to the neural retina. It is a key gene in the Ngn2-regulated neuronal differentiation pathway, coordinating the onset of cortical gene transcription. This gene also regulates amacrine cell fate determination in the retina. [provided by RefSeq, Jul 2016]

Expression: Biased expression in CNS E11.5 (RPKM 1.8), CNS E14 (RPKM 0.6) and 4 other tissues

Gene size: 12103bp

Exon count: 2