Full name: arginase type II

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: AII

Summary: Predicted to enable arginase activity; manganese ion binding activity; and nitric-oxide synthase binding activity. Involved in several processes, including negative regulation of CD4-positive, alpha-beta T cell proliferation; negative regulation of activated CD8-positive, alpha-beta T cell apoptotic process; and negative regulation of cytokine production. Acts upstream of or within striated muscle contraction and ureteric bud development. Located in mitochondrion. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Human ortholog(s) of this gene implicated in asthma. Orthologous to human ARG2 (arginase 2). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Biased expression in duodenum adult (RPKM 66.9), small intestine adult (RPKM 62.2) and 8 other tissues

Gene size: 25514bp

Exon count: 8