Full name: ankyrin 3, epithelial

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: 2900054D09Rik; Ank-3; AnkG; Ankyrin-3; Ankyrin-G

Summary: This gene encodes a member of the ankyrin protein family. Ankyrins link integral membrane proteins to the spectrin-based cytoskeleton. Ankyrin family members share a protein structure which includes three independently folded domains: the N-terminal ankyrin repeat domain, the central spectrin-binding domain, and the C-terminal rod domain. This ankyrin functions as the major ankyrin in the kidney and may play a role in the polarized distribution of many integral membrane proteins to specific subcellular sites. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Expression: Broad expression in cerebellum adult (RPKM 12.9), CNS E18 (RPKM 10.5) and 16 other tissues

Gene size: 628659bp

Exon count: 57