Full name: bromodomain, testis-specific

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: 7420412D09Rik; Brd6; Fsrg3

Summary: The protein encoded by this gene belongs to the BET protein family. BET proteins have two N-terminal bromodomains and one C-terminal extraterminal domain (ET domain). BET proteins regulate chromatin reorganization via binding to acetylated histones. This gene is thought to play a role in the transcriptional regulation of spermatogenesis. Although referred to as testis-specific bromodomain (Brdt) protein, RT-PCR indicates that this gene is expressed in both mouse oocytes and testes. Alternative splicing results in multiple transcript variants encoding different proteins. [provided by RefSeq, Jul 2008]

Expression: Biased expression in testis adult (RPKM 12.3), cortex adult (RPKM 1.6) and 6 other tissues

Gene size: 55946bp

Exon count: 23