TOE1 target of EGR1, exonuclease [ Homo sapiens (human) ]
Source: NCBI Gene (ID 114034)
Source: NCBI Gene (ID 114034)
Symbol: TOE1
Full name: target of EGR1, exonuclease
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Homo sapiens
Also known as: PCH7; TOE-1; hCaf1z
Summary: Enables poly(A)-specific ribonuclease activity and snRNA binding activity. Involved in RNA phosphodiester bond hydrolysis, exonucleolytic and snRNA 3'-end processing. Located in Cajal body and cytoplasm. Implicated in pontocerebellar hypoplasia type 7. [provided by Alliance of Genome Resources, Apr 2022]
Expression: Ubiquitous expression in testis (RPKM 7.9), bone marrow (RPKM 5.3) and 25 other tissues
Orthologs: mouse
Gene size: 3804bp
Exon count: 8