Abcb7 ATP-binding cassette, sub-family B (MDR/TAP), member 7 [ Mus musculus (house mouse) ] - Gene - Data resources

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Abcb7 ATP-binding cassette, sub-family B (MDR/TAP), member 7 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 11306)

Symbol: Abcb7

Full name: ATP-binding cassette, sub-family B (MDR/TAP), member 7

Gene type: protein coding

RefSeq status: VALIDATED

Organism: Mus musculus

Also known as: Abc7

Summary: Predicted to enable ABC-type iron-sulfur cluster transporter activity and protein homodimerization activity. Involved in iron-sulfur cluster assembly; positive regulation of heme biosynthetic process; and positive regulation of iron-sulfur cluster assembly. Acts upstream of or within cellular iron ion homeostasis. Located in mitochondrial inner membrane. Is expressed in several structures, including adrenal gland; central nervous system; gut; hemolymphoid system gland; and retina. Human ortholog(s) of this gene implicated in X-linked sideroblastic anemia with ataxia. Orthologous to human ABCB7 (ATP binding cassette subfamily B member 7). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Ubiquitous expression in liver E14 (RPKM 4.5), cerebellum adult (RPKM 4.1) and 27 other tissues

Orthologs: human

Gene size: 133282bp

Exon count: 16