Full name: DNA polymerase iota

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: RAD30B; RAD3OB; eta2

Summary: The protein encoded by this gene is an error-prone DNA polymerase involved in DNA repair. The encoded protein promotes DNA synthesis across lesions in the template DNA, which other polymerases cannot do. The encoded polymerase inserts deoxynucleotides across lesions and then relies on DNA polymerase zeta to extend the nascent DNA strand to bypass the lesion. [provided by RefSeq, May 2017]

Expression: Ubiquitous expression in thyroid (RPKM 9.1), testis (RPKM 7.6) and 25 other tissues

Gene size: 51788bp

Exon count: 14