NUDT4 nudix hydrolase 4 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 11163)
Symbol: NUDT4
Full name: nudix hydrolase 4
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Also known as: DIPP-2B; DIPP2; DIPP2alpha; DIPP2beta; HDCMB47P; NUDT4B
Summary: The protein encoded by this gene regulates the turnover of diphosphoinositol polyphosphates. The turnover of these high-energy diphosphoinositol polyphosphates represents a molecular switching activity with important regulatory consequences. Molecular switching by diphosphoinositol polyphosphates may contribute to regulating intracellular trafficking. Several alternatively spliced transcript variants have been described, but the full-length nature of some variants has not been determined. Isoforms DIPP2alpha and DIPP2beta are distinguishable from each other solely by DIPP2beta possessing one additional amino acid due to intron boundary skidding in alternate splicing. [provided by RefSeq, Jul 2008]
Expression: Ubiquitous expression in ovary (RPKM 30.0), kidney (RPKM 25.7) and 25 other tissues
Orthologs: mouse
Gene size: 30222bp
Exon count: 7