Timp4 tissue inhibitor of metalloproteinase 4 [ Mus musculus (house mouse) ] - Gene - Data resources

110595

Timp4 tissue inhibitor of metalloproteinase 4 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 110595)

Symbol: Timp4

Full name: tissue inhibitor of metalloproteinase 4

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: Timp-4

Summary: Predicted to enable metalloendopeptidase inhibitor activity and protease binding activity. Acts upstream of or within Notch signaling pathway. Predicted to be located in sarcomere. Predicted to be active in extracellular matrix and extracellular space. Is expressed in several structures, including brain ventricular layer; heart; ovary; skin; and ventral grey horn. Human ortholog(s) of this gene implicated in nephroblastoma. Orthologous to human TIMP4 (TIMP metallopeptidase inhibitor 4). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Biased expression in genital fat pad adult (RPKM 71.5), subcutaneous fat pad adult (RPKM 64.7) and 8 other tissues

Orthologs: human

Gene size: 7762bp

Exon count: 5