Full name: kallikrein related peptidase 11

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: PRSS20; TLSP

Summary: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing and the use of alternate promoters results in multiple transcript variants encoding distinct isoforms which are differentially expressed. [provided by RefSeq, Dec 2016]

Expression: Biased expression in esophagus (RPKM 58.7), skin (RPKM 44.2) and 7 other tissues

Gene size: 5756bp

Exon count: 9