Full name: WASP family member 3

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: Brush-1; SCAR3; WAVE3

Summary: This gene encodes a member of the Wiskott-Aldrich syndrome protein family. The gene product is a protein that forms a multiprotein complex that links receptor kinases and actin. Binding to actin occurs through a C-terminal verprolin homology domain in all family members. The multiprotein complex serves to tranduce signals that involve changes in cell shape, motility or function. A pseudogene of this gene have been defined on chromosome 6. Alternative splicing results in multiple transcript variants [provided by RefSeq, May 2014]

Expression: Broad expression in brain (RPKM 34.0), fat (RPKM 12.7) and 15 other tissues

Gene size: 149810bp

Exon count: 15