NCKAP1 NCK associated protein 1 [ Homo sapiens (human) ] - Gene - Data resources

10787

NCKAP1 NCK associated protein 1 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 10787)

Symbol: NCKAP1

Full name: NCK associated protein 1

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: HEM2; NAP1; NAP125; p125Nap1

Summary: Contributes to small GTPase binding activity. Involved in Rac protein signal transduction; positive regulation of Arp2/3 complex-mediated actin nucleation; and positive regulation of lamellipodium assembly. Located in extracellular exosome and focal adhesion. Part of SCAR complex. [provided by Alliance of Genome Resources, Apr 2022]

Expression: Ubiquitous expression in thyroid (RPKM 62.7), brain (RPKM 61.6) and 24 other tissues

Orthologs: mouse

Gene size: 129343bp

Exon count: 32