STAG2 stromal antigen 2 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 10735)
Source: NCBI Gene (ID 10735)
Symbol: STAG2
Full name: stromal antigen 2
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Also known as: HPE13; MKMS; NEDXCF; SA-2; SA2; SCC3B; bA517O1.1
Summary: The protein encoded by this gene is a subunit of the cohesin complex, which regulates the separation of sister chromatids during cell division. Targeted inactivation of this gene results in chromatid cohesion defects and aneuploidy, suggesting that genetic disruption of cohesin is a cause of aneuploidy in human cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]
Expression: Ubiquitous expression in thyroid (RPKM 24.4), bone marrow (RPKM 22.3) and 25 other tissues
Orthologs: mouse
Gene size: 142097bp
Exon count: 40