Full name: peroxiredoxin 4

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: AOE37-2; AOE372; HEL-S-97n; PRX-4

Summary: The protein encoded by this gene is an antioxidant enzyme and belongs to the peroxiredoxin family. The protein is localized to the cytoplasm. Peroxidases of the peroxiredoxin family reduce hydrogen peroxide and alkyl hydroperoxides to water and alcohol with the use of reducing equivalents derived from thiol-containing donor molecules. This protein has been found to play a regulatory role in the activation of the transcription factor NF-kappaB. [provided by RefSeq, Jul 2008]

Expression: Ubiquitous expression in pancreas (RPKM 49.0), liver (RPKM 22.7) and 25 other tissues

Gene size: 18905bp

Exon count: 7