Full name: KLF transcription factor 2

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: LKLF

Summary: This gene encodes a protein that belongs to the Kruppel family of transcription factors. The encoded zinc finger protein is expressed early in mammalian development and is found in many different cell types. The protein acts to bind the CACCC box found in the promoter of target genes to activate their transcription. It plays a role in many processes during development and disease including adipogenesis, embryonic erythropoiesis, epithelial integrity, inflammation and t-cell viability. [provided by RefSeq, Mar 2017]

Expression: Broad expression in fat (RPKM 40.2), ovary (RPKM 23.1) and 19 other tissues

Gene size: 3860bp

Exon count: 3