KATNB1 katanin regulatory subunit B1 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 10300)
Source: NCBI Gene (ID 10300)
Symbol: KATNB1
Full name: katanin regulatory subunit B1
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Also known as: KAT; LIS6
Summary: Microtubules, polymers of alpha and beta tubulin subunits, form the mitotic spindle of a dividing cell and help to organize membranous organelles during interphase. Katanin is a heterodimer that consists of a 60 kDa ATPase (p60 subunit A 1) and an 80 kDa accessory protein (p80 subunit B 1). The p60 subunit acts to sever and disassemble microtubules, while the p80 subunit targets the enzyme to the centrosome. Katanin is a member of the AAA family of ATPases. [provided by RefSeq, Jul 2008]
Expression: Broad expression in testis (RPKM 14.6), brain (RPKM 7.5) and 24 other tissues
Orthologs: mouse
Gene size: 21475bp
Exon count: 20