MAEA macrophage erythroblast attacher, E3 ubiquitin ligase [ Homo sapiens (human) ]
Source: NCBI Gene (ID 10296)
Source: NCBI Gene (ID 10296)
Symbol: MAEA
Full name: macrophage erythroblast attacher, E3 ubiquitin ligase
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Also known as: EMLP; EMP; GID9; HLC-10; P44EMLP; PIG5
Summary: This gene encodes a protein that mediates the attachment of erythroblasts to macrophages. This attachment promotes terminal maturation and enucleation of erythroblasts, presumably by suppressing apoptosis. The encoded protein is an integral membrane protein with the N-terminus on the extracellular side and the C-terminus on the cytoplasmic side of the cell. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Expression: Ubiquitous expression in kidney (RPKM 10.3), spleen (RPKM 10.0) and 25 other tissues
Orthologs: mouse
Gene size: 50247bp
Exon count: 13