Hsd3b7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 101502)
Source: NCBI Gene (ID 101502)
Symbol: Hsd3b7
Full name: hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Summary: Enables cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity. Involved in B cell chemotaxis. Predicted to be located in intracellular membrane-bounded organelle and lipid droplet. Is expressed in several structures, including alimentary system; bladder; facial bone primordium; heart; and liver and biliary system. Human ortholog(s) of this gene implicated in congenital bile acid synthesis defect 1 and intrahepatic cholestasis. Orthologous to human HSD3B7 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in liver adult (RPKM 369.2), liver E18 (RPKM 105.2) and 11 other tissues
Orthologs: human
Gene size: 3195bp
Exon count: 8